Open positions:

Ph.D. and post-doctoral applications are always welcome from suitably qualified, highly motivated individuals. Please send your application directly to Ryan Gilmour.


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  Fluorinated Organocatalysts for the Enantioselective Epoxidation of Enals: Molecular Pre-organisation by the Fluorine-Iminium Ion Gauche Effect.

E.-M. Tanzer, L. E. Zimmer, W. B. Schweizer and R. Gilmour, Chem. Eur. J. 2012, accepted for publication.

Selected as a Very Important Paper (VIP)

  Exploiting Fluorine Conformational Effects in Organocatalyst Design: The Fluorine-Iminium Ion Gauche Effect

C. Sparr, L. E. Zimmer and R. Gilmour, in Asymmetric Synthesis: More Methods and Applications, (Eds. M. Christmann and S. Bräse), Wiley-VCH, 2012, in print.


Fluorine-Directed β-Galactosylation: Chemical Glycosylation Development by Molecular Editing

E. Durantie, C. Bucher, and R. Gilmour, Chem. Eur. J. 2012, 18, 8208–8215.


  Designing Fluorinated Cinchona Alkaloids for Enantioselective Catalysis: Controlling Internal Rotation by a Fluorine-Ammonium Ion Gauche Effect (ϕNCCF)

E.-M. Tanzer, W. B. Schweizer, M.-O. Ebert and R. Gilmour, Chem. Eur. J., 2012, 18, 2006–2013.

  Fundamental Insights into the Enantioselectivity of Hydrogenations on Cinchona-Modified Platinum and Palladium

E. Schmidt, C. Bucher, G. Santarossa, T. Mallat, R. Gilmour, A. Baiker, J. Catal. 2012, 289, 238–248.

  DL-Ribose Crystal Structures: the Glass-Crystal Transformation.

G. Zandomeneghi, W. B. Schweizer, R. Gilmour, B. H. Meier, J. D. Dunitz, Helv. Chim. Acta 2012, accepted for publication (in honour of Prof. Dieter Seebach's 75th birthday)



  Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design

L. E. Zimmer, C. Sparr and R. Gilmour, Angew. Chem. 2011, 123, 12062-12074; Angew. Chem. Int. Ed. 2011, 50, 11860-11871.

  Cyclopropyl Iminium Activation: Reactivity Umpolung in Enantioselective Organocatalytic Reaction Design

C. Sparr and R. Gilmour, Angew. Chem. 2011, 123, 8541-8545; Angew. Chem. Int. Ed. 2011, 50, 8391-8395.

Selected as a Hot Paper by Angewandte Chemie.

  Theoretical and X-ray Crystallographic Evidence of a Fluorine-Imine Gauche Effect: An Addendum to Dunathan's Stereoelectronic Hypothesis

C. Sparr, E. Salamanova, W. B. Schweizer, H. M. Senn and R. Gilmour, Chem. Eur. J. 2011, 17, 8850-8857.

  Conference Report: The 46th EUCHEM Conference on Stereochemistry (Bürgenstock Conference 2011)

L. J. Prins and R. Gilmour, Chimia 2011, in press.

  Homage to Vladimir Prelog

R. Gilmour, Chemistry World, April 2011 (book review).

  Steering Glycosylation with the C-F Bond

C. Bucher and R. Gilmour, Synlett 2011, 1043-1046.
Invited contribution.

  A Modular Synthesis of Fluorinated, Chiral Polar Lipids

C. Bucher and R. Gilmour, Synthesis 2011, 549-552.



  A Novel Fluorinated Au(I) N-Heterocyclic Carbene Complex: Exploiting Fluorine Stereoelectronic Effects to Control Molecular Topology

S. Paul, W. B. Schweizer, M.-O. Ebert and R. Gilmour, Organometallics 2010, 29, 4424-4427.

  Fluorine-Directed Glycosylation

C. Bucher and R. Gilmour, Angew. Chem. 2010, 122, 8906-8910; Angew. Chem. Int. Ed. 2010, 49, 8724-8728.
Highlighted in Chimia 2011, 65, 874.

  Fluoro-Organocatalysts: Conformer Equivalents as a Tool for Mechanistic Studies

C. Sparr and R. Gilmour, Angew. Chem. 2010, 122, 6670-6673; Angew. Chem. Int. Ed. 2010, 49, 6520-6523.

Selected as a Hot Paper by Angewandte Chemie.
Highlighted in Synfacts 2010, 1193: Using Fluorine to 'Freeze Out' Catalyst Conformations and in Chimia 2010, 64, 824.

  A Novel Class of Fluorinated Cinchona Alkaloids as Surface Modifiers for the Heterogeneous Platinum-Catalysed Enantioselective Hydrogenation of α-Ketoesters

C. Bucher, C. Mondelli, A. Baiker and R. Gilmour, J. Mol. Catal. A: Chem. 2010, 327, 87-91.

  The Crystal Structure of D-Ribose – At Last!

D. Šišak, L. B. McCusker, G. Zandomeneghi, B. Meier, D. Bläser, R. Boese, W. B. Schweizer, R. Gilmour and J. D. Dunitz, Angew. Chem. 2010, 122, 4605-4608; Angew. Chem. Int. Ed. 2010, 49, 4503-4505.

  Stereochemical Models for Discussing Additions to α,β-Unsaturated Aldehydes
Organocatalysed by Diarylprolinol or Imidazolidinone Derivatives – is there
an E/Z-Dilemma?

D. Seebach, R. Gilmour, U. Grošelj, G. Deniau, C. Sparr, M.-O. Ebert and A. K. Beck, Helv. Chim. Acta 2010, 93, 603-634.

  A Concise Synthesis of (S)-2-(Fluorodiphenylmethyl)pyrrolidine: A Novel Organocatalyst for the Stereoselective Epoxidation of α,β-Unsaturated Aldehydes

C. Sparr, E.-M. Tanzer, J. Bachmann and R. Gilmour, Synthesis 2010, 1394-1397.



  Fluorinated Quinine Alkaloids: Synthesis, X-ray Structure Analysis and Anti-Malarial Parasite Chemotherapy

C. Bucher, C. Sparr, W. B. Schweizer and R. Gilmour, Chem. Eur. J. 2009, 15, 7637-7647.

Highlighted in Malaria World (Nr. 220).

  The Fluorine-Iminium Ion Gauche Effect: Proof of Principle and Application to Asymmetric Organocatalysis.

C. Sparr, W. B. Schweizer, H. M. Senn and R. Gilmour, Angew. Chem. 2009, 121, 3111-3114; Angew. Chem. Int. Ed. 2009, 48, 3065-3068.

Highlighted in Synfacts 2009, 673: A Fluorinated "Designer" Organocatalyst and in Chimia 2009, 63, 349.


Masters, Doctoral and Post-Doctoral Publications

  Total Syntheses of Amphidinolides B1, B4, G1, H1 and Structural Revision of Amphidinolide H2.

A. Fürstner, L. C. Bouchez, L. Morency, J.-A. Funel, V. Liepins, F.-H. Poree, R. Gilmour, D. Laurich, F. Beaufils, and M. Tamiya, Chem. Eur. J. 2009, 15, 3983-4010.




The Handbook of Chemical Glycosylation: Advances in Stereoselectivity and Therapeutic Relevance.

R. Gilmour and P. H. Seeberger, J. Am. Chem. Soc. 2008, 130, 11241 (book review).

  Safe, facile radical-based reduction and hydrosilylation reactions in a microreactor using tris(trimethylsilyl)silane.

A. Odedra, K. Geyer, T. Gustafsson, R. Gilmour and P. H. Seeberger, Chem. Commun. 2008, 3025-3027.

  Fluorination reactions in microreactors.

T. Gustafsson, R. Gilmour and P. H. Seeberger, Chem. Commun. 2008, 3022-3024.

  Structural diversity in imidazolidinone organocatalysts: a synchrotron and computational study.

J. C. Burley, R. Gilmour, T. J. Prior and G. M. Day, Acta Cryst. 2008, C64, o10-o14.




The Development of a High-Throughput, Microarray-Based Synthesis of Natural Product Analogs via In Vitro Pathway Construction.

R. Gilmour and P. H. Seeberger, ChemTracts 2007, 191-198.


Total Syntheses of Amphidinolide H and G.

A. Fürstner, L. C. Bouchez, J.-A. Funel, V. Liepins, F.-H. Porée, R. Gilmour, F. Beaufils, D. Laurich and M. Tamiya, Angew. Chem. 2007, 119, 9425-9430; Angew. Chem. Int. Ed. 2007, 46, 9265-9270.


An organocatalytic approach to the core of eunicellin.

R. Gilmour, T. J. Prior, J. W. Burton and A. B. Holmes, Chem. Commun. 2007, 3954-3956.




The Synthesis and Biological Evaluation of Novel Eunicellin Analogues.

J.E. P. Davidson, R. Gilmour, S. Ducki, J. E. Davies, R. Green, J. W. Burton and A. B. Holmes, Synlett (Heathcock Edition) 2004, 8, 1434-1436.




Synthetic studies related to diketopyrrolopyrrole (DPP) pigments. Part 1: The search for alkenyl-DPPs. Unsaturated nitriles in standard DPP syntheses: a novel cyclopenta[c]pyrrolone chromophore.

C. J. H. Morton, R. Gilmour, D. M. Smith, P. Lightfoot, A. M. Z. Slawin and E. J. MacLean, Tetrahedron 2002, 58, 5547-5565.


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© 2014 ETH Zurich | Imprint | Disclaimer | 28 July 2012