printlogo
http://www.ethz.ch/index_EN
Welcome
 
print
  

Publications:

Open positions:

Ph.D. and post-doctoral applications are always welcome from suitably qualified, highly motivated individuals. Please send your application directly to Ryan Gilmour.

Firefox:

If you are having trouble viewing this page please download the latest edition of Firefox.

firefox
 

2012

     
  Fluorinated Organocatalysts for the Enantioselective Epoxidation of Enals: Molecular Pre-organisation by the Fluorine-Iminium Ion Gauche Effect.

E.-M. Tanzer, L. E. Zimmer, W. B. Schweizer and R. Gilmour, Chem. Eur. J. 2012, accepted for publication.

Selected as a Very Important Paper (VIP)

EMT_Bildgrose_andern
     
  Exploiting Fluorine Conformational Effects in Organocatalyst Design: The Fluorine-Iminium Ion Gauche Effect

C. Sparr, L. E. Zimmer and R. Gilmour, in Asymmetric Synthesis: More Methods and Applications, (Eds. M. Christmann and S. Bräse), Wiley-VCH, 2012, in print.

Book_chapter_Bildgrose_andern
     

Fluorine-Directed β-Galactosylation: Chemical Glycosylation Development by Molecular Editing

E. Durantie, C. Bucher, and R. Gilmour, Chem. Eur. J. 2012, 18, 8208–8215.

glyco2012

     
  Designing Fluorinated Cinchona Alkaloids for Enantioselective Catalysis: Controlling Internal Rotation by a Fluorine-Ammonium Ion Gauche Effect (ϕNCCF)

E.-M. Tanzer, W. B. Schweizer, M.-O. Ebert and R. Gilmour, Chem. Eur. J., 2012, 18, 2006–2013.

EMT
     
  Fundamental Insights into the Enantioselectivity of Hydrogenations on Cinchona-Modified Platinum and Palladium

E. Schmidt, C. Bucher, G. Santarossa, T. Mallat, R. Gilmour, A. Baiker, J. Catal. 2012, 289, 238–248.

bucher2012
     
  DL-Ribose Crystal Structures: the Glass-Crystal Transformation.

G. Zandomeneghi, W. B. Schweizer, R. Gilmour, B. H. Meier, J. D. Dunitz, Helv. Chim. Acta 2012, accepted for publication (in honour of Prof. Dieter Seebach's 75th birthday)

dl
dl
     
 

2011

     
  Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design

L. E. Zimmer, C. Sparr and R. Gilmour, Angew. Chem. 2011, 123, 12062-12074; Angew. Chem. Int. Ed. 2011, 50, 11860-11871.

Review
     
  Cyclopropyl Iminium Activation: Reactivity Umpolung in Enantioselective Organocatalytic Reaction Design

C. Sparr and R. Gilmour, Angew. Chem. 2011, 123, 8541-8545; Angew. Chem. Int. Ed. 2011, 50, 8391-8395.

Selected as a Hot Paper by Angewandte Chemie.

cp
     
  Theoretical and X-ray Crystallographic Evidence of a Fluorine-Imine Gauche Effect: An Addendum to Dunathan's Stereoelectronic Hypothesis

C. Sparr, E. Salamanova, W. B. Schweizer, H. M. Senn and R. Gilmour, Chem. Eur. J. 2011, 17, 8850-8857.

imb
     
  Conference Report: The 46th EUCHEM Conference on Stereochemistry (Bürgenstock Conference 2011)

L. J. Prins and R. Gilmour, Chimia 2011, in press.

     
  Homage to Vladimir Prelog

R. Gilmour, Chemistry World, April 2011 (book review).




  Steering Glycosylation with the C-F Bond

C. Bucher and R. Gilmour, Synlett 2011, 1043-1046.
Invited contribution.

d
     
  A Modular Synthesis of Fluorinated, Chiral Polar Lipids

C. Bucher and R. Gilmour, Synthesis 2011, 549-552.

pol
     
 

2010

     
  A Novel Fluorinated Au(I) N-Heterocyclic Carbene Complex: Exploiting Fluorine Stereoelectronic Effects to Control Molecular Topology

S. Paul, W. B. Schweizer, M.-O. Ebert and R. Gilmour, Organometallics 2010, 29, 4424-4427.

sp
     
  Fluorine-Directed Glycosylation

C. Bucher and R. Gilmour, Angew. Chem. 2010, 122, 8906-8910; Angew. Chem. Int. Ed. 2010, 49, 8724-8728.
Highlighted in Chimia 2011, 65, 874.

40
     
  Fluoro-Organocatalysts: Conformer Equivalents as a Tool for Mechanistic Studies

C. Sparr and R. Gilmour, Angew. Chem. 2010, 122, 6670-6673; Angew. Chem. Int. Ed. 2010, 49, 6520-6523.

Selected as a Hot Paper by Angewandte Chemie.
Highlighted in Synfacts 2010, 1193: Using Fluorine to 'Freeze Out' Catalyst Conformations and in Chimia 2010, 64, 824.

32
     
  A Novel Class of Fluorinated Cinchona Alkaloids as Surface Modifiers for the Heterogeneous Platinum-Catalysed Enantioselective Hydrogenation of α-Ketoesters

C. Bucher, C. Mondelli, A. Baiker and R. Gilmour, J. Mol. Catal. A: Chem. 2010, 327, 87-91.

25
     
  The Crystal Structure of D-Ribose – At Last!

D. Šišak, L. B. McCusker, G. Zandomeneghi, B. Meier, D. Bläser, R. Boese, W. B. Schweizer, R. Gilmour and J. D. Dunitz, Angew. Chem. 2010, 122, 4605-4608; Angew. Chem. Int. Ed. 2010, 49, 4503-4505.

45
     
  Stereochemical Models for Discussing Additions to α,β-Unsaturated Aldehydes
Organocatalysed by Diarylprolinol or Imidazolidinone Derivatives – is there
an E/Z-Dilemma?

D. Seebach, R. Gilmour, U. Grošelj, G. Deniau, C. Sparr, M.-O. Ebert and A. K. Beck, Helv. Chim. Acta 2010, 93, 603-634.

13
     
  A Concise Synthesis of (S)-2-(Fluorodiphenylmethyl)pyrrolidine: A Novel Organocatalyst for the Stereoselective Epoxidation of α,β-Unsaturated Aldehydes

C. Sparr, E.-M. Tanzer, J. Bachmann and R. Gilmour, Synthesis 2010, 1394-1397.

8
     

2009

     
  Fluorinated Quinine Alkaloids: Synthesis, X-ray Structure Analysis and Anti-Malarial Parasite Chemotherapy

C. Bucher, C. Sparr, W. B. Schweizer and R. Gilmour, Chem. Eur. J. 2009, 15, 7637-7647.

Highlighted in Malaria World (Nr. 220).

10
     
  The Fluorine-Iminium Ion Gauche Effect: Proof of Principle and Application to Asymmetric Organocatalysis.

C. Sparr, W. B. Schweizer, H. M. Senn and R. Gilmour, Angew. Chem. 2009, 121, 3111-3114; Angew. Chem. Int. Ed. 2009, 48, 3065-3068.

Highlighted in Synfacts 2009, 673: A Fluorinated "Designer" Organocatalyst and in Chimia 2009, 63, 349.

angew_fluor
     
 

Masters, Doctoral and Post-Doctoral Publications

     
  Total Syntheses of Amphidinolides B1, B4, G1, H1 and Structural Revision of Amphidinolide H2.

A. Fürstner, L. C. Bouchez, L. Morency, J.-A. Funel, V. Liepins, F.-H. Poree, R. Gilmour, D. Laurich, F. Beaufils, and M. Tamiya, Chem. Eur. J. 2009, 15, 3983-4010.

9
     
 

2008

     

The Handbook of Chemical Glycosylation: Advances in Stereoselectivity and Therapeutic Relevance.

R. Gilmour and P. H. Seeberger, J. Am. Chem. Soc. 2008, 130, 11241 (book review).

     
  Safe, facile radical-based reduction and hydrosilylation reactions in a microreactor using tris(trimethylsilyl)silane.

A. Odedra, K. Geyer, T. Gustafsson, R. Gilmour and P. H. Seeberger, Chem. Commun. 2008, 3025-3027.

5
     
  Fluorination reactions in microreactors.

T. Gustafsson, R. Gilmour and P. H. Seeberger, Chem. Commun. 2008, 3022-3024.

6
     
  Structural diversity in imidazolidinone organocatalysts: a synchrotron and computational study.

J. C. Burley, R. Gilmour, T. J. Prior and G. M. Day, Acta Cryst. 2008, C64, o10-o14.

7
     

2007

     

The Development of a High-Throughput, Microarray-Based Synthesis of Natural Product Analogs via In Vitro Pathway Construction.

R. Gilmour and P. H. Seeberger, ChemTracts 2007, 191-198.

     

Total Syntheses of Amphidinolide H and G.

A. Fürstner, L. C. Bouchez, J.-A. Funel, V. Liepins, F.-H. Porée, R. Gilmour, F. Beaufils, D. Laurich and M. Tamiya, Angew. Chem. 2007, 119, 9425-9430; Angew. Chem. Int. Ed. 2007, 46, 9265-9270.

4
     

An organocatalytic approach to the core of eunicellin.

R. Gilmour, T. J. Prior, J. W. Burton and A. B. Holmes, Chem. Commun. 2007, 3954-3956.

3
     

2004

     

The Synthesis and Biological Evaluation of Novel Eunicellin Analogues.

J.E. P. Davidson, R. Gilmour, S. Ducki, J. E. Davies, R. Green, J. W. Burton and A. B. Holmes, Synlett (Heathcock Edition) 2004, 8, 1434-1436.

2
     

2002

     

Synthetic studies related to diketopyrrolopyrrole (DPP) pigments. Part 1: The search for alkenyl-DPPs. Unsaturated nitriles in standard DPP syntheses: a novel cyclopenta[c]pyrrolone chromophore.

C. J. H. Morton, R. Gilmour, D. M. Smith, P. Lightfoot, A. M. Z. Slawin and E. J. MacLean, Tetrahedron 2002, 58, 5547-5565.

1
     
 

Wichtiger Hinweis:
Diese Website wird in älteren Versionen von Netscape ohne graphische Elemente dargestellt. Die Funktionalität der Website ist aber trotzdem gewährleistet. Wenn Sie diese Website regelmässig benutzen, empfehlen wir Ihnen, auf Ihrem Computer einen aktuellen Browser zu installieren. Weitere Informationen finden Sie auf
folgender Seite.

Important Note:
The content in this site is accessible to any browser or Internet device, however, some graphics will display correctly only in the newer versions of Netscape. To get the most out of our site we suggest you upgrade to a newer browser.
More information

© 2014 ETH Zurich | Imprint | Disclaimer | 28 July 2012
top